| Coaches | |
|---|---|
| Position | Name |
| Head Coach | Mike Macdonald |
| Offensive Coordinator | Klint Kubiak |
| Defensive Coordinator | Aden Durde |
| Special Teams Coach | Jay Harbaugh |
| Offense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | NO | Player 4 | NO | Player 5 |
| QB | 14 | Sam Darnold | NA | Jalen Milroe(R) | 6 | Drew Lock | ||||
| RB | 9 | Kenneth Walker III | 26 | Zach Charbonnet | 25 | Kenny McIntosh | NA | Damien Martinez(R) | 36 | George Holani |
| LWR | 10 | Cooper Kupp | NA | Tory Horton(R) | 85 | River Cracraft | NA | Tyrone Broden(R) | ||
| SWR | 11 | Jaxon Smith-Njigba | NA | Ricky White III(R) | 84 | Steven Sims | 17 | John Rhys Plumlee | ||
| RWR | 1 | Marquez Valdes-Scantling | 19 | Jake Bobo | 83 | Dareke Young | 82 | Cody White | ||
| TE | 87 | Noah Fant | NA | Elijah Arroyo(R) | 88 | AJ Barner | NA | Robbie Ouzts(R) | 38 | Brady Russell |
| LT | 67 | Charles Cross | 74 | Josh Jones | NA | Amari Kight(R) | ||||
| LG | NA | Grey Zabel(R) | 63 | Sataoa Laumea | NA | Mason Richman(R) | NA | AJ Gillie(R) | ||
| C | 55 | Olu Oluwatimi | 61 | Jalen Sundell | NA | Federico Maranges(R) | ||||
| RG | 75 | Anthony Bradford | 64 | Christian Haynes | NA | Bryce Cabeldue(R) | ||||
| RT | 72 | Abraham Lucas | 65 | Michael Jerrell | 70 | Malaesala Aumavae-Laulu | ||||
| Defense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | NO | Player 4 | NO | Player 5 |
| DE | 99 | Leonard Williams | 94 | Mike Morris | NA | Jared Ivey(R) | NA | TJ Jackson III(R) | ||
| DT | 90 | Jarran Reed | NA | Rylie Mills(R) | NA | J.R. Singleton(R) | ||||
| NT | 91 | Byron Murphy II | 92 | Quinton Bohanna | 95 | Brandon Pili | NA | Wy'Kevious Thomas(R) | ||
| WLB | 13 | Ernest Jones | 47 | Josh Ross | 52 | Patrick O'Connell | ||||
| MLB | 48 | Tyrice Knight | 42 | Drake Thomas | NA | Jackson Woodard(R) | ||||
| LOLB | NA | Demarcus Lawrence | 53 | Boye Mafe | 59 | Tyreke Smith | NA | Connor O'Toole(R) | NA | Jalen Gaines(R) |
| ROLB | 7 | Uchenna Nwosu | 58 | Derick Hall | 44 | Jamie Sheriff | NA | Seth Coleman(R) | ||
| LCB | 29 | Josh Jobe | 28 | Nehemiah Pritchett | 35 | JT Woods | NA | Isaiah Hamilton(R) | ||
| RCB | 27 | Riq Woolen | 34 | Shemar Jean-Charles | NA | Zy Alexander(R) | NA | Isas Waxter(R) | ||
| SS | 20 | Julian Love | NA | Nick Emmanwori(R) | 32 | Jerrick Reed II | ||||
| FS | 8 | Coby Bryant | 23 | D'Anthony Bell | 30 | AJ Finley | 39 | Ty Okada | ||
| NB | 21 | Devon Witherspoon | 37 | Damarion Williams | 33 | Tyler Hall | ||||
| Special Teams | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | ||||
| P | 4 | Michael Dickson | ||||||||
| K | 5 | Jason Myers | ||||||||
| LS | 41 | Chris Stoll | ||||||||
| PR | 84 | Steven Sims | ||||||||
| KR | 84 | Steven Sims | 25 | Kenny McIntosh | ||||||
| H | 4 | Michael Dickson | ||||||||
| KO | 5 | Jason Myers | ||||||||
